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In recent years, there has been a growing interest in leveraging Deep Reinforcement Learning (DRL) to tackle the complexities of portfolio optimization. Despite its potential, a notable limitation of DRL algorithms is their inherent difficulty in integrating conflicted objectives with the reward functions throughout the learning process. Typically, DRL's reward function prioritizes the maximization of returns or other performance indicators, often overlooking the integration of risk aspects. Furthermore, the standard DRL framework struggles to incorporate practical constraints, such as cardinality and bounding, into the decision process. Without these constraints, the investment strategies developed might be unrealistic and unmanageable. To this end, in this paper, we propose an adaptive and safe DRL framework, which can dynamically optimize the portfolio weights while strictly respecting practical constraints. In our method, any infeasible action (i.e., one that violates the constraints) decided by the RL agent will be mapped to a feasible region using a safety layer. The extended Markowitz Mean-Variance (M-V) model is explicitly encoded in the safety layer to ensure the feasibility of the actions from the alternative views. In addition, we utilize Projection-based Interior-point Policy Optimization (IPO) to resolve multiple objectives and constraints in the examined problem. 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