[{"data":1,"prerenderedAt":376},["ShallowReactive",2],{"publication-2024\u002Fautomatic-quantitative-stroke-severity-assessment-based-on-chinese-clinical-name-en":3,"publication-members":63},{"_path":4,"_dir":5,"_draft":6,"_partial":6,"_locale":7,"title":8,"description":9,"_hidden":6,"named entity recognition with domain-adaptive pre-trained large language model authors":10,"authors_orcid":21,"year":32,"doi":33,"openalex_id":34,"venue":35,"abstract_screenshot":27,"keywords":36,"body":43,"_type":56,"_id":57,"_source":58,"_file":59,"_stem":60,"_extension":61,"locale":62},"\u002Fpublications\u002F2024\u002Fautomatic-quantitative-stroke-severity-assessment-based-on-chinese-clinical-name","2024",false,"","Automatic quantitative stroke severity assessment based on Chinese clinical","BACKGROUND: Stroke is a prevalent disease with a significant global impact. Effective assessment of stroke severity is vital for an accurate diagnosis, appropriate treatment, and optimal clinical outcomes. The National Institutes of Health Stroke Scale (NIHSS) is a widely used scale for quantitatively assessing stroke severity. However, the current manual scoring of NIHSS is labor-intensive, time-consuming, and sometimes unreliable. Applying artificial intelligence (AI) techniques to automate the quantitative assessment of stroke on vast amounts of electronic health records (EHRs) has attracted much interest. OBJECTIVE: This study aims to develop an automatic, quantitative stroke severity assessment framework through automating the entire NIHSS scoring process on Chinese clinical EHRs. METHODS: Our approach consists of two major parts: Chinese clinical named entity recognition (CNER) with a domain-adaptive pre-trained large language model (LLM) and automated NIHSS scoring. To build a high-performing CNER model, we first construct a stroke-specific, densely annotated dataset \"Chinese Stroke Clinical Records\" (CSCR) from EHRs provided by our partner hospital, based on a stroke ontology that defines semantically related entities for stroke assessment. We then pre-train a Chinese clinical LLM coined \"CliRoberta\" through domain-adaptive transfer learning and construct a deep learning-based CNER model that can accurately extract entities directly from Chinese EHRs. Finally, an automated, end-to-end NIHSS scoring pipeline is proposed by mapping the extracted entities to relevant NIHSS items and values, to quantitatively assess the stroke severity. RESULTS: Results obtained on a benchmark dataset CCKS2019 and our newly created CSCR dataset demonstrate the superior performance of our domain-adaptive pre-trained LLM and the CNER model, compared with the existing benchmark LLMs and CNER models. The high F1 score of 0.990 ensures the reliability of our model in accurately extracting the entities for the subsequent automatic NIHSS scoring. Subsequently, our automated, end-to-end NIHSS scoring approach achieved excellent inter-rater agreement (0.823) and intraclass consistency (0.986) with the ground truth and significantly reduced the processing time from minutes to a few seconds. CONCLUSION: Our proposed automatic and quantitative framework for assessing stroke severity demonstrates exceptional performance and reliability through directly scoring the NIHSS from diagnostic notes in Chinese clinical EHRs. Moreover, this study also contributes a new clinical dataset, a pre-trained clinical LLM, and an effective deep learning-based CNER model. The deployment of these advanced algorithms can improve the accuracy and efficiency of clinical assessment, and help improve the quality, affordability and productivity of healthcare services.",[11,12,13,14,15,16,17,18,19,20],"Gu, Zhanzhong","He, Xiangjian","Yu, Ping","Jia, Wenjing","Yang, Xiguang","Peng, Gang","Hu, Penghui","Chen, Shiyan","Chen, Hongjie","Lin, Yiguang",[22,23,24,25,26,27,28,29,30,31],"0000-0002-0628-5575","0000-0001-8962-540X","0000-0002-7910-9396","0000-0002-0940-3338","0000-0002-6441-6836",null,"0000-0003-3876-2732","0000-0002-4195-3014","0009-0009-8968-2047","0000-0002-4637-9701",2024,"https:\u002F\u002Fdoi.org\u002F10.1016\u002Fj.artmed.2024.102822","W4392202585","Artificial Intelligence in Medicine",[37,38,39,40,41,42],"Computer science","Artificial intelligence","Natural language processing","Domain (mathematical analysis)","Stroke (engine)","Machine learning",{"type":44,"children":45,"toc":53},"root",[46],{"type":47,"tag":48,"props":49,"children":50},"element","p",{},[51],{"type":52,"value":9},"text",{"title":7,"searchDepth":54,"depth":54,"links":55},2,[],"markdown","content:publications:2024:automatic-quantitative-stroke-severity-assessment-based-on-chinese-clinical-name.md","content","publications\u002F2024\u002Fautomatic-quantitative-stroke-severity-assessment-based-on-chinese-clinical-name.md","publications\u002F2024\u002Fautomatic-quantitative-stroke-severity-assessment-based-on-chinese-clinical-name","md","en",[64,77,82,93,100,108,114,123,130,136,141,151,158,167,173,185,194,203,209,217,222,230,236,244,248,258,265,273,278,287,293,301,307,315,320,326,336,344,350,358,363,371],{"_path":65,"title":66,"name":67,"role":68,"email":27,"image":69,"category":70,"interests":71,"order":54,"_id":76},"\u002Fmembers\u002Fstaff\u002Falain-chong","Vice President for Global Affairs and Partnerships · Professor of Information Systems and Digital Innovation","Alain Chong","Deputy Director of Lab","assets\u002F8.png","staff",[72,73,74,75],"信息系统与运作管理","计算机科学与运筹学","Information Systems and Operations Management","Computer Science and Operations Research","content:members:staff:alain-chong.md",{"_path":65,"title":78,"role":79,"interests":80,"_id":81},"全球事务与合作副校长 · 信息系统与数字创新教授","实验室副主任",[72,73],"content:members:staff:alain-chong.zh-CN.md",{"_path":83,"title":84,"name":85,"role":86,"email":27,"image":87,"category":70,"interests":88,"order":91,"_id":92},"\u002Fmembers\u002Fstaff\u002Fanthony-belloti","Professor","Anthony Belloti","Core Member","assets\u002F41.png",[89,90],"Machine Learning and Credit Risk Model","Model Risks",9,"content:members:staff:anthony-belloti.md",{"_path":83,"title":94,"role":95,"interests":96,"_id":99},"计算机科学系教授","核心成员",[97,98],"机器学习与信用风险模型","模型风险","content:members:staff:anthony-belloti.zh-CN.md",{"_path":101,"title":102,"name":102,"role":86,"email":27,"image":103,"category":70,"interests":104,"order":106,"_id":107},"\u002Fmembers\u002Fstaff\u002Fboon-giin-lee","Boon Giin Lee","assets\u002F31.jpg",[105],"Intelligent Sensor and Extended Reality",11,"content:members:staff:boon-giin-lee.md",{"_path":101,"title":109,"role":95,"interests":110,"_id":113},"人机交互实验室负责人 · 计算机科学系副教授",[111,112],"人机交互 HCI","智能传感与扩展现实技术","content:members:staff:boon-giin-lee.zh-CN.md",{"_path":115,"title":116,"name":116,"role":117,"email":27,"image":118,"category":70,"interests":119,"order":121,"_id":122},"\u002Fmembers\u002Fstaff\u002Fcong-cao","Cong Cao","Direction Leader","assets\u002FCC.png",[120],"Science and technology policy and institutional reform",7,"content:members:staff:cong-cao.md",{"_path":115,"title":124,"name":125,"role":126,"interests":127,"_id":129},"宁波诺丁汉大学商学院创新学教授","曹聪","方向带头人",[128],"科技政策与体制改革","content:members:staff:cong-cao.zh-CN.md",{"_path":131,"title":132,"name":132,"role":86,"email":27,"image":133,"category":70,"order":134,"_id":135},"\u002Fmembers\u002Fstaff\u002Fdave-towey","Dave Towey","assets\u002F32.jpg",8,"content:members:staff:dave-towey.md",{"_path":131,"title":137,"role":95,"interests":138,"_id":140},"计算机科学系教授 · 计算机科学系主任",[139],"计算机科学与语言学","content:members:staff:dave-towey.zh-CN.md",{"_path":142,"title":143,"name":143,"role":86,"email":27,"image":144,"category":70,"interests":145,"order":149,"_id":150},"\u002Fmembers\u002Fstaff\u002Ffazl-ullah-khan","Fazl Ullah Khan","assets\u002F44.png",[146,147,148],"Computer Network","Computer Architecture and Network Security","Software Engineering",12,"content:members:staff:fazl-ullah-khan.md",{"_path":142,"title":152,"role":95,"interests":153,"_id":157},"计算机科学系助理教授 · IEEE 高级会员",[154,155,156],"计算机网络","计算机和网络安全","软件工程","content:members:staff:fazl-ullah-khan.zh-CN.md",{"_path":159,"title":160,"name":161,"role":86,"email":27,"image":162,"category":70,"interests":163,"order":165,"_id":166},"\u002Fmembers\u002Fstaff\u002Fheng-yu","Associate Professor","Heng Yu","assets\u002FHENGYU.png",[164],"Embedded Systems Design",17,"content:members:staff:heng-yu.md",{"_path":159,"title":168,"name":169,"role":95,"interests":170,"_id":172},"计算机科学系副教授","于恒",[171],"嵌入式系统设计","content:members:staff:heng-yu.zh-CN.md",{"_path":174,"title":160,"name":175,"role":86,"email":27,"image":176,"category":70,"interests":177,"order":183,"_id":184},"\u002Fmembers\u002Fstaff\u002Fheshan-du","Heshan Du","assets\u002Fhesahndu.png",[178,179,180,181,182],"Logic, Knowledge Representation and Reasoning","Geographic Information Systems","Operations Research","Machine Learning","Reinforcement Learning",20,"content:members:staff:heshan-du.md",{"_path":174,"title":168,"name":186,"role":95,"interests":187,"_id":193},"杜何珊",[188,189,190,191,192],"逻辑与知识表示","地理信息系统","运筹学","机器学习","强化学习","content:members:staff:heshan-du.zh-CN.md",{"_path":195,"title":196,"name":197,"role":86,"email":27,"image":198,"category":70,"interests":199,"order":201,"_id":202},"\u002Fmembers\u002Fstaff\u002Fhuan-jin","Assistant Professor","Huan Jin","assets\u002Fhuanjin.png",[200,181],"Optimisation",21,"content:members:staff:huan-jin.md",{"_path":195,"title":204,"name":205,"role":95,"interests":206,"_id":208},"计算机科学系助理教授","靳欢",[207,191],"优化","content:members:staff:huan-jin.zh-CN.md",{"_path":210,"title":160,"name":211,"role":117,"email":27,"image":212,"category":70,"interests":213,"order":215,"_id":216},"\u002Fmembers\u002Fstaff\u002Fjianfeng-ren","Jianfeng Ren","assets\u002F42.jpg",[181,214],"Computer Vision",3,"content:members:staff:jianfeng-ren.md",{"_path":210,"title":168,"name":218,"role":126,"interests":219,"_id":221},"任剑锋",[191,220],"计算机视觉","content:members:staff:jianfeng-ren.zh-CN.md",{"_path":223,"title":224,"name":224,"role":117,"email":27,"image":225,"category":70,"interests":226,"order":228,"_id":229},"\u002Fmembers\u002Fstaff\u002Fjiawei-li","Jiawei Li","assets\u002F11.png",[227],"Computer Science and Artificial Intelligence",15,"content:members:staff:jiawei-li.md",{"_path":223,"title":231,"name":232,"role":126,"interests":233,"_id":235},"计算机科学系助理教授 · 英国诺丁汉大学博士后","李家炜",[234],"计算机与人工智能","content:members:staff:jiawei-li.zh-CN.md",{"_path":237,"title":160,"name":238,"role":86,"email":27,"image":239,"category":70,"interests":240,"order":242,"_id":243},"\u002Fmembers\u002Fstaff\u002Fmatthew-pike","Matthew Pike","assets\u002F43.jpg",[241],"Digitalised Learning",16,"content:members:staff:matthew-pike.md",{"_path":237,"title":168,"role":95,"interests":245,"_id":247},[246],"数字化学习","content:members:staff:matthew-pike.zh-CN.md",{"_path":249,"title":196,"name":250,"role":86,"email":27,"image":251,"category":70,"interests":252,"order":256,"_id":257},"\u002Fmembers\u002Fstaff\u002Fning-xue","Ning Xue","\u002Fimages\u002Fuon-logo.png",[253,254,255],"Artificial Intelligence","Computational Intelligence","Combinatorial Optimization",13,"content:members:staff:ning-xue.md",{"_path":249,"title":204,"name":259,"role":95,"interests":260,"_id":264},"薛宁",[261,262,263],"人工智能","计算智能","组合优化","content:members:staff:ning-xue.zh-CN.md",{"_path":266,"title":196,"name":267,"role":86,"email":27,"image":268,"category":70,"interests":269,"order":271,"_id":272},"\u002Fmembers\u002Fstaff\u002Fqian-zhang","Qian Zhang","assets\u002Fqz.png",[270,214,181],"Image Processing",14,"content:members:staff:qian-zhang.md",{"_path":266,"title":204,"name":274,"role":95,"interests":275,"_id":277},"张茜",[276,220,191],"图像处理","content:members:staff:qian-zhang.zh-CN.md",{"_path":279,"title":84,"name":280,"role":281,"email":27,"image":282,"category":70,"interests":283,"orcid":284,"order":285,"_id":286},"\u002Fmembers\u002Fstaff\u002Fruibin-bai","Ruibin Bai","Director of Lab","assets\u002F38.png",[75],"0000-0003-1722-568X",1,"content:members:staff:ruibin-bai.md",{"_path":279,"title":288,"name":289,"role":290,"interests":291,"_id":292},"教授","白瑞斌","实验室主任",[73],"content:members:staff:ruibin-bai.zh-CN.md",{"_path":294,"title":295,"name":295,"role":117,"email":27,"image":296,"category":70,"interests":297,"order":299,"_id":300},"\u002Fmembers\u002Fstaff\u002Fsean-he","Sean He","assets\u002F39.png",[214,298,181],"Data Analytics",5,"content:members:staff:sean-he.md",{"_path":294,"title":302,"name":303,"role":126,"interests":304,"_id":306},"计算机科学系教授 · 国家级讲席学者","何祥健",[220,305,191],"数据分析","content:members:staff:sean-he.zh-CN.md",{"_path":308,"title":309,"name":309,"role":86,"email":27,"image":310,"category":70,"interests":311,"order":313,"_id":314},"\u002Fmembers\u002Fstaff\u002Ftianxiang-cui","Tianxiang Cui","assets\u002Ftianxiangcui.png",[254,312,181,182],"Operation Research",19,"content:members:staff:tianxiang-cui.md",{"_path":308,"title":152,"name":316,"role":95,"interests":317,"_id":319},"崔天翔",[262,318,191,192],"运筹研究","content:members:staff:tianxiang-cui.zh-CN.md",{"_path":321,"title":84,"name":322,"role":86,"email":27,"image":323,"category":70,"order":324,"_id":325},"\u002Fmembers\u002Fstaff\u002Fxiuping-hua","Xiuping Hua","assets\u002FxiupignHua.png",10,"content:members:staff:xiuping-hua.md",{"_path":321,"title":327,"name":328,"role":95,"interests":329,"_id":335},"金融、会计与经济系教授","华秀萍",[330,331,332,333,334,97],"资产定价","公司金融","衍生品","金融科技","创新金融和普惠金融","content:members:staff:xiuping-hua.zh-CN.md",{"_path":337,"title":84,"name":338,"role":86,"email":27,"image":339,"category":70,"interests":340,"order":342,"_id":343},"\u002Fmembers\u002Fstaff\u002Fying-weng","Ying Weng","assets\u002Fyingweng.png",[214,270,341],"IoT",4,"content:members:staff:ying-weng.md",{"_path":337,"title":94,"name":345,"role":95,"interests":346,"_id":349},"翁莹",[220,276,347,348],"物联网 IoT","无线网络安全与服务质量","content:members:staff:ying-weng.zh-CN.md",{"_path":351,"title":196,"name":352,"role":86,"email":27,"image":353,"category":70,"interests":354,"order":356,"_id":357},"\u002Fmembers\u002Fstaff\u002Fyuan-yao","Yuan Yao","assets\u002Fyuanyao.png",[355],"Autonomous Agents and Multi-Agent Systems",18,"content:members:staff:yuan-yao.md",{"_path":351,"title":204,"name":359,"role":95,"interests":360,"_id":362},"姚远",[361],"自主智能体与多智能体系统","content:members:staff:yuan-yao.zh-CN.md",{"_path":364,"title":196,"name":365,"role":117,"email":27,"image":366,"category":70,"interests":367,"order":369,"_id":370},"\u002Fmembers\u002Fstaff\u002Fzheng-lu","Zheng Lu","assets\u002F13.png",[368],"Computer Science",6,"content:members:staff:zheng-lu.md",{"_path":364,"title":204,"name":372,"role":126,"interests":373,"_id":375},"卢正",[374],"计算机科学","content:members:staff:zheng-lu.zh-CN.md",1782639592748]